Week 6 in the NFL was as unpredictable as ever, as a changing of the guard seems to be upon us in the league. Tom Brady and Aaron Rodgers are both .500 or worse this late in the season for the first time since 2012, and the New York teams are a combined 9-3.The Giants are 5-1 for the first time since 2009, while the Jets have their best start to a season since 2015. The Jets matched their win total from last season while the Giants pa sed it -- in just six games. The have Jonathan Toews Jersey lost consecutive games in the regular season for the first time in four years and suffered their worst lo s ever under Rodgers at Lambeau Field.Plenty of overreactions are in store for Week 6. Let's see if these are deserved or need to be dialed down a bit.Overreaction or reality:RealitySunday's win over the wasn't big in determining the favorite coming out of the AFC, but the road to the Super Bowl will likely be going though Buffalo. The Bills defeated the Chiefs at Arrowhead Stadium and have pulled off wins in two straight one-score games, so that hex on the Super Bowl contenders is gone. Buffalo is the only one-lo s team in the conference and owns the head-to-head tiebreaker over Kansas City. The Bills are the clear favorite in the AFC East and own a two-game lead on the and a one-game lead over the emerging Jets. They also beat the Ravens earlier this year (and Baltimore is 3-3 after six games).The road to the Super Bowl in the AFC looks like it'll go through Orchard Park in January. That's a scary thought.Overreaction or reality: OverreactionHere's the biggest i sue with the 49ers. How many injuries can this team withstand? On San Francisco's defense, and are the only two starters that didn't suffer an injury during Sunday's lo s to the , nor had an injury prior to the game. left the game with a groin injury. had to be evaluated for a concu sion (but did return), and left with a leg injury (he returned as well). , , , , , and all mi sed the game with various injuries.The 49ers defense didn't overcome their injuries in the lo s to the Falcons, but Henri Jokiharju Jersey this team has the depth to withstand the injuries (and have through the majority of the year). San Francisco will eventually get some of these players back and make a run at the NFC West.Overreaction or reality: RealityZappe has made two starts with the Patriots, and New England has averaged 33.5 points per game and 381.5 yards per game in those starts. They are also 2-0 in the two starts under Zappe. The fourth-round rookie went 24 of 34 for 309 yards with two touchdowns and no interceptions in Sunday's win over the , actually finding both his tight ends ( and ) six times for 122 yards and a touchdown. Not only did the Patriots throw for 301 yards, but they were 7 of 14 on third down and 2 of 3 in goal-to-go situations. Zappe has four touchdowns to one interception and a 111.4 pa ser rating this season, with a 72.9% completion rate. He's the first rookie quarterback in the Super Bowl era to win and post a 100-plus pa ser rating in each of his first two starts.Bottom line: Zappe has done more than enough to warrant another start (at least). The Patriots offense is better with him at quarterback.Overreaction or reality: RealityNew York is 4-2 and just handed Green Bay its largest lo s under at Lambeau Field. already looks like one of the most explosive players in the , and the defense is shining with , , and leading the way. The Jets have the look of a playoff team, finding different ways to beat opponents every week. The offensive line does a good job of protecting , and the defense continues to improve, allowing under 300 yards for the third straight week.If the AFC had to pick seven teams to make the playoffs, the Jets would be one of them.Overreaction or reality:RealityIndianapolis had its best game from its wide receivers in Sunday's win over Jacksonville. finished with 13 catches for 134 yards to lead the way Chicago Blackhawks Jersey , but the biggest contribution came from rookie . The second-round pick caught a 32-yard touchdown pa s from with 17 seconds left to get the Colts to 3-2-1 on the year, the fourth straight week he's had a significant contribution to the offense. also had seven catches for 57 yards and a touchdown. Ryan's chemistry is growing with his wideouts, as he's thrown for 996 yards and five touchdowns over the past three weeks. If Sunday's game carries over, the Colts may not have to add another wide receiver at the trade deadline.Pittman, Pierce, and Campbell are good enough. Pick Six Newsletter Crafted By The Best NFL Experts Get the day's big stories + fun stuff you love like mock drafts, picks and power rankings. I agree to receive the "Pick Six Newsletter" and marketing communications, updates, special offers (including partner offers), and other information from CBS Sports and the Paramount family of companies. By pre sing sign up, Bobby Hull Jersey I confirm that I have read and agree to the . Please check the opt-in box to acknowledge that you would like to subscribe. Thanks for signing up! Keep an eye on your inbox. Sorry! There was an error proce sing your subscription. Overreaction or reality:OverreactionHard to not be in favor of a 5-1 start, especially since the Vikings have built a commanding lead in the NFC North. Minnesota is one of just three five-win teams in the NFC and four five-win teams in the entire NFL. The Vikings did lose to the , but that was over a month ago. They haven't lost since.Minnesota certainly capitalized on Miami's miscues, as a bobbled ball led to a interception and an eventual field goal. Waddle's fumble after a long catch late led to another Miami turnover -- taking more potential points off the board in a 17-16 game. The Vikings got 10 points off Waddle's miscues. The Vikings are a good team, albeit in a mediocre division. They are not in the Super Bowl contending tier yet.Overreaction or reality:RealityWhat the Saints were able to do on the ground against the was impre sive. New Orleans rushed for 228 yards and averaged 6.7 yards per carry against a Bengals defense that allowed 99.6 rushing yards per game and just one rushing touchdown on the year.Without their top three wide receivers, the game plan should have been easy for the Bengals defense. A healthy ran for 99 yards while added 46 on the ground and had 39. Rookie also had a 44-yard touchdown run. Even when the Denis Savard Jersey playmaking pa s catchers come back, offensive coordinator Pete Carmichael Jr. should dial back the pa s and commit to the run more. The Saints are a better running team than they might have thought.Overreaction or reality:RealityThe are 5-1 and already have more wins then they had all of last year. A healthy helps, but New York is winning with and a subpar offensive line. Beating the is another excellent win for an emerging Gi